Renal Involvement in Systemic Sclerosis: An Update
نویسندگان
چکیده
منابع مشابه
Systemic sclerosis: an update.
Systemic sclerosis (SSc) is a complex and heterogeneous chronic illness characterized by substantial patient to patient variability in clinical manifestations, internal organ involvement, and outcome. Genetic factors contribute to disease susceptibility, but environmental influences also play a significant role. The pathogenesis of SSc encompasses vascular, immunological, and fibrotic processes...
متن کاملSystemic Sclerosis - An Update
Systemic sclerosis (SSc) is a clinically heterogeneous, systemic disorder affecting connective tissue of skin, internal organs, and walls of blood vessels. It is characterized by alterations of the microvasculature in the form of hypoxia, digital ulcers, and pulmonary arterial hypertension; disturbances of the immune system, including dysbalance of cytokine expression, autoantibodies (Auto-ab),...
متن کامل[An update on systemic sclerosis].
Systemic sclerosis affects multiple internal organs and systems and is characterized by high clinical variability. Early diagnosis of the disease itself and of organ involvement plays a key role in the management of systemic sclerosis. The prognosis for each patient is equally important. In recent years there has been significant progress in our understanding of the pathogenesis and clinical co...
متن کاملAssociation between atherosclerosis and parenchymal lung involvement in systemic sclerosis
Background: Systemic sclerosis is an autoimmune disease affecting connective tissues, (including epidermal, subepidermal, microvasculature, etc.), leading to various extent of end-organ damage. The leading cause of mortality among these patients is lung involvement. The cardiovascular events happen more frequently in patients suffering systemic scleroderma, comparing to healthy population. This...
متن کاملGenetics of Systemic Sclerosis: An Update
Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune cell activation, and fibrosis of the skin and internal organs. Over the past few years, a role for genetics in the susceptibility for SSc has been established. This review aims to provide an update on the progress made in the past year or so within the field of SSc genetics research. This year has been of pa...
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ژورنال
عنوان ژورنال: Kidney and Blood Pressure Research
سال: 2020
ISSN: 1420-4096,1423-0143
DOI: 10.1159/000507886